Fictitious content. The figures below are theoretical constructs for teaching purposes. They do not describe any real product, market, or person, and no real patient data is used or published anywhere in this tool.
Model structure
HIQA applies one discount rate to costs and outcomes alike; custom values are allowed.
Without the correction, the model assumes everyone changes state on the very last day of a cycle, so a full cycle of cost and quality of life is credited to whoever is left at the end. On average people move around the middle of the cycle instead, so each state is counted as the average of its start and end membership — effectively half a cycle at the beginning and end of time spent there. Toggle it off to see how much the results shift.
Transition probabilities per cycle
UncoverDx-guided gene therapy
Standard of care
State costs
UncoverDx-guided gene therapy
Standard of care
Utility weights (QALY)
UncoverDx-guided gene therapy
Standard of care